John Locke (Terry O’Quinn), a middle aged man confined to a wheelchair after falling out of a window while fighting his father who had conned his way back into John’s life and suckered him into giving him a kidney.
After spending four years in a wheelchair, John decides to travel to Australia for a Walkabout but is denied the right to do so by a Melbourne Travel Tour Agent. Defiant, John shouts, “Don’t tell me what I can’t do. Ever!”
Returning to America, John boards Oceanic Flight 815 from Sydney to Los Angeles which later crashes on a mysterious remote Pacific island where John is miraculously healed and can suddenly walk again. He soon becomes a leader among the surviving passengers of the doomed flight.